PARACRINE INDUCTION OF EPITHELIAL-MESENCHYMAL TRANSITION BETWEEN COLORECTAL CANCER CELLS AND ITS SUPPRESSION BY A P53/MIR-192/215/NID1 AXISSUMMARY

Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 AxisSummary

Background & Aims: Intratumor heterogeneity is a common feature of colorectal cancer (CRC).Here, we analyzed whether mesenchymal-like CRC cells promote the progression of epithelial-like CRC cells via paracrine mechanisms.Methods: Six CRC cell lines that show an epithelial phenotype were treated with conditioned media (CM) from CRC cell lines that

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Public key searchable encryption scheme based on blockchain

Aiming at the trapdoor security problem of the public key encryption scheme,a random number constructing trapdoor and index was introduced to defend against keyword guessing attacks from the server and avoid data leakage caused by server curious behavior.Research on trusted issues of third parties,the blockchain mechanism with a searchable encrypti

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Materialized Genealogy: From Anonymous Cemetery Populations to Creating Alternative Narratives about Individuals and Family Burial Space

Archaeologists frequently excavate historic burials and the vast majority of the graves will be unidentified.It is rare, and also WILD ORCHID surprisingly difficult, to unite documentary sources and gravestone identities with the burials underneath.Sites are therefore interpreted and analyzed as holistic anonymous populations rather than as individ

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